Clinical Applications of a 450 nm Blue Diode Laser in Oral Soft Tissue Surgery and Submandibular Calculus Management: A Series of Three Cases
Salvatore Luca La Terra1*, Francesco Buoncristiani2, Gianluigi Caccianiga3, Faisal Alzahrani4,5, Naief AL Dweesh6
1Department of Translational Medicine, University of Ferrara, Ferrara, Italy. Private Dental Clinic, Rome and Ragusa, Italy.
2Department of Oral Surgery, "Buoncristiani" Private Dental Clinic, San Vincenzo (LI), Italy.
3Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
4Department of Oral Surgery, Ulster University and College of Medicine and Dentistry, Birmingham, United Kingdom.
5Department of Oral and Maxillofacial Surgery, Royal Armed Forces Hospital Southern Region, Khamis Mushait, Saudi Arabia.
6Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, United Kingdom.
*Corresponding Author: Dr. Salvatore Luca La Terra, DDS, MSc, PhD by Research, PgCert, PgDip, Department of Translational Medicine, University of Ferrara, Ferrara, Italy. Private Dental Clinic, Rome and Ragusa, Italy.
https://doi.org/10.58624/SVOADE.2026.07.030
Received: June 17, 2026
Published: July 03, 2026
Citation: La Terra SL, Buoncristiani F, Caccianiga G, Alzahrani F, AL Dweesh N. Clinical Applications of a 450 nm Blue Diode Laser in Oral Soft Tissue Surgery and Submandibular Calculus Management: A Series of Three Cases. SVOA Dentistry 2026, 7:4, 220-231. doi: 10.58624/SVOADE.2026.07.030
Abstract
Background: Conventional near-infrared diode lasers (810-980 nm) are widely used in oral soft tissue surgery but may produce collateral thermal effects due to deeper tissue penetration. The 450 nm blue diode laser exhibits higher absorption by hemoglobin and melanin, potentially enabling more precise incision, effective hemostasis, and reduced thermal injury. This case series evaluated its clinical application in selected oral soft tissue lesions and laser-assisted access for submandibular calculus removal.
Methods: Three patients with giant cell fibroma, oral squamous papilloma, and submandibular calculus respectively, were treated using a 450 nm blue diode laser (1 W, continuous-wave mode, contact mode, 200 μm fiber tip). Outcomes assessed included intraoperative bleeding, procedure duration, need for suturing, postoperative pain (visual analogue scale [VAS]), healing time, complications, recurrence, patient satisfaction, and operator-related outcomes.
Results: Complete treatment was done in all cases without intraoperative complications. Excellent hemostasis was observed, and no sutures were required. Mean operative time was 5.33±0.47 minutes. Mean VAS pain scores were 2.33±0.47 at 24 hours and 1.00±0.00 at 3 days. Complete healing occurred within 7-9 days (mean: 8.0±0.82 days). No infections, delayed healing, neurosensory disturbances, complications, or recurrence were observed during the 6-month follow-up period. Patient satisfaction and operator-rated visibility were consistently high.
Conclusion: The 450 nm blue diode laser demonstrated favourable clinical performance in selected oral soft tissue procedures and laser-assisted access for the removal of submandibular calculus. Precise tissue incision, effective hemostasis, low postoperative discomfort, and uneventful healing were consistently observed. Further, controlled clinical studies are required to validate these findings.
Keywords: 450 nm Diode Laser; Blue Diode Laser; Oral Soft Tissue Surgery; Giant Cell Fibroma; Oral Squamous Papilloma; Sialolithiasis; Submandibular Sialolith; Hemostasis.
