Gingival Overgrowth Caused by Amlodipine: Case Report
Carlos Alberto Cabrini Júnior1, Celso Augusto Lemos Junior2, Elio Hitoshi Shinohara3, Irineu Gregnanin Pedron4*
1DDS, Postgraduate Student in Endodontics, School of Dentistry, University of Sa o Paulo, Private practice, Sao Paulo, Brazil.
2DDS, MDS, PhD. Associate Professor, Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil.
3DDS, PhD, Independent Researcher, Private practice, Sao Paulo, Brazil.
4DDS, MDS. Professor, Department of Periodontics and Integrated Clinic, Faculty of Dentistry, Universidade Braz Cubas, Mogi das Cruzes, Brazil.
*Corresponding Author: Irineu Gregnanin Pedron, DDS, MDS. Professor, Department of Periodontics and Integrated Clinic, Faculty of Dentistry, Universidade Braz Cubas, Mogi das Cruzes, Brazil.
https://doi.org/10.58624/SVOADE.2025.06.023
Received: August 14, 2025
Published: August 26, 2025
Citation: Cabrini Jr CA, Lemos Jr CA, Shinohara EH, Pedron IG. Gingival Overgrowth Caused by Amlodipine: Case Report. SVOA Dentistry 2025, 6:5, 139-144. doi: 10.58624/ SVOADE.2025.06.023
Abstract
Patients with special needs often require medication to control and treat systemic diseases. Hypertensive patients usually receive various types of drugs, among which amlodipine stands out as an antihypertensive medication. Amlodipine can have several side effects. In the stomatognathic system, gingival overgrowth may require special care in its management. The purpose of this article was to present the case of a hypertensive patient under amlodipine administration who developed gingival overgrowth. Surgical treatment was performed for its removal, and the cardiologist was requested to replace the medication. The clinical and histopathological features, incidence and frequency, diagnosis, and therapeutic modalities of gingival overgrowth caused by amlodipine were discussed.
Keywords: Amlodipine; Gingival Overgrowth; Hypertension; Periodontal Diseases; Dentistry.
