Cerebral Vein Thrombosis Induced by Short-Term Oral Contraceptive Use: A Case Report
Edward Darielle Dominguez González1*, Cruz Manuel Alvarez-Fraire2, Juan Carlos Tun Piste3, Juan Pablo Colli Heredia4
1Internal Medicine Residency Program, Hospital de Especialidades Campeche “Dr. Javier Buenfil Osorio”, Campeche, 24050, Mexico.
2Internal Medicine Residency Program, Hospital de Especialidades Campeche “Dr. Javier Buenfil Osorio”, Campeche, 24050, Mexico.
3Internal Medicine Residency Program, Hospital de Especialidades Campeche “Dr. Javier Buenfil Osorio”, Campeche, 24050, Mexico.
4Head of Internal Medicine Program, Hospital de Especialidades Campeche “Dr. Javier Buenfil Osorio”, Campeche, 24050, Mexico.
*Corresponding Author: Edward Darielle Domí nguez Gonza lez, Internal Medicine Residency Program, Hospital de Especialidades Campeche “Dr. Javier Buenfil Osorio”, Campeche, 24050, Mexico.
https://doi.org/10.58624/SVOAMR.2025.03.018
Received: September 25, 2025
Published: October 09, 2025
Citation: Dominguez Gonzalez ED, Alvarez-Fraire CM, Tun Piste JC, Colli Heredia JP. Cerebral Vein Thrombosis Induced by Short-Term Oral Contraceptive Use: A Case Report. SVOA Medical Research 2025, 3:5, 167-171. doi: 10.58624/SVOAMR.2025.03.018
Abstract
Background: Cerebral venous thrombosis (CVT) is increasingly recognized in young adults, although oral contraceptive pills increase the risk of CVT, cerebral venous involvement is relatively uncommon, particularly when exposure is short-term.
Case Presentation: A 32-year-old woman was referred from a private medical center with a 12-day history of headache and right-predominant lower limb weakness. She had a history of miscarriage two months prior to symptom onset, after which she began oral contraceptive pills. This led to the development of cerebral venous thrombosis, with clinical improvement following oral anticoagulation therapy.
Conclusions: The clinical manifestations of cerebral venous thrombosis are heterogeneous. However, the onset of headache and lower limb weakness should raise suspicion of CVT, especially in women with a recent history of oral contraceptive use.
Keywords: Cerebral venous thrombosis, Oral contraceptives, Female